| Year | Date | Historical Events |
| 1958 | Apr 15 | Launched. |
| | Aug 30 | Commissioned. |
| 1959 | Feb 19 | Arrived at the Naval Air Station, Roosevelt Roads, R.R. after training exercises off the east coast. After making a brief run back to Portsmouth, she returned to the Caribbean to train in launching Regulus I & II guided missiles. |
| | Sep 7 | Arrived at Pearl Harbor to serve as flagship of Submarine Division 12 participating in a variety of battle and torpedo exercises as well as missile practice before beginning her 1st Regulu Deterrent Mission. |
| 1960 | Mar 12 | Departed Hawaii with a full store of Regulus II sea-to-surface missiles, armed with nuclear warheads to patrol under a strict cloak of secrecy. |
| 1961 | May 1 | Began her history of 9 deterrent mission patrols. The 4th terminated at Yokosuka, Japan as the Navy proudly displayed one of its newest and most effective weapons. |
| 1964 | May 25 | Decommissioned. |