| Year | Date | Historical Events |
| 1919 | Nov 7 | Keel laid down at the Bethlehem Shipbuilding Corp., Quincy,MA. |
| 1922 | Oct 22 | Launched. |
| 1923 | Oct 15 | Commissioned with LT. Edmund W. Burrough in command. Operating out of New London, CT., from 1923 into 1925, S-26 visited St. Thomas and Trinidad from January into April 1924, and Hawaii from 27 April to 30 May 1925.
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| 1930 | Dec 1 | S-26 departed San Diego,CA. |
| | Dec 12 | S-26 arrived at Pearl Harbor, HI. |
| 1938 | Oct 15 | S-26 departed Pearl Harbor, HI. |
| 1939 | Mar 25 | S-26 arrived at New London,CT. |
| 1941 | Dec 10 | S-26 departed New London,CT. |
| | Dec 19 | S-26 arrived at Coco Solo, Canal Zone. |
| 1942 | Jan 24 | Rammed by PC-460 at night in the Gulf of Panama, S-26 sank on 24 January 1942 with the loss of 46 men Two men survived. Her hull was not salvaged. |
| | Jan 24 | Rammed by PC-460 at night in the Gulf of Panama, S-26 sank on 24 January 1942 with the loss of 46 men Two men survived. Her hull was not salvaged. |